STRUCTURAL INSIGHTS INTO A HIGHLY FLEXIBLE ZINC FINGER MODULE UNRAVEL INSM1 FUNCTION IN TRANSCRIPTION REGULATION

Structural insights into a highly flexible zinc finger module unravel INSM1 function in transcription regulation

Abstract Orderly development of neuroendocrine and nervous system of mammals requires INSM1, a key regulator for cell differentiation.Ectopic expression of INSM1 is closely correlated with human neuroendocrine tumorigenesis, which makes INSM1 a reliable diagnostic biomarker and potential therapeutic target.To date, INSM1 is known as a transcription

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A simulation-based evaluation of methods for estimating census population size of terrestrial game species from genetically-identified parent-offspring pairs

Estimates of wildlife population size are critical for conservation and management, but accurate estimates are difficult to obtain for many species.Several methods have recently been developed that estimate abundance using kinship relationships observed in genetic samples, particularly parent-offspring pairs.While these methods are similar to tradi

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In vitro thermotherapy-based methods for plant virus eradication

Abstract Production of virus-free plants is necessary to control viral diseases, import novel cultivars from other countries, exchange breeding materials between Adult Apron countries or regions and preserve plant germplasm.In vitro techniques represent the most successful approaches for virus eradication.In vitro thermotherapy-based methods, inclu

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